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1

Covalent coupling of doxorubicin in protein microspheres is a major determinant of tumour drug disposition

Jeffrey Cummings, Neville Willmott, Elaine Marley, John Smyth

Journal:

Biochemical Pharmacology

Year:

1991

Language:

english

File:

PDF, 656 KB

english, 1991

2

Relationship between reductive drug metabolism in tumour tissue of anthracyclines in microspherical form and anti-tumour activity

Neville Willmott, Jeffrey Cummings, Elaine Marley, John F. Smyth

Journal:

Biochemical Pharmacology

Year:

1990

Language:

english

File:

PDF, 702 KB

english, 1990

3

Incorporation and Release of Chemically Intact Mitomycin C from Albumin Microspheres: a High Performance Liquid Chromatography Evaluation

Allan, Lucy, Cummings, Jeffrey, Willmott, Neville, Whateley, Tony, Smyth, John

Journal:

Journal of Drug Targeting

Year:

1993

Language:

english

File:

PDF, 973 KB

english, 1993

4

Adriamycin-loaded albumin microspheres: qualitative assessment of drug incorporation and in vitro release by high-performance liquid chromatography and high-speed multi-diode array spectrophotometric detection

Jeffrey Cummings, Neville Willmott

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1985

Language:

english

File:

PDF, 372 KB

english, 1985

5

Effect of matrix metalloproteinase inhibitors on tumor growth and spontaneous metastasis

James G. Conway, Suzanne J. Trexler, Jean A. Wakefield, Brian E. Marron, David L. Emerson, David M. Bickettf, David N. Deaton, Deanna Garrison, Mike Elder, Andy McElroy, Neville Willmott, Andrew J. P.

Journal:

Clinical and Experimental Metastasis

Year:

1996

Language:

english

File:

PDF, 880 KB

english, 1996

6

Alchemy in cancer

WILLMOTT, NEVILLE

Journal:

Year:

1981

File:

PDF, 142 KB

1981

7

Increased anti-tumor effect of adriamycin-loaded albumin microspheres is associated with anaerobic bioreduction of drug in tumor tissue

Neville Willmott, Jeffrey Cummings

Journal:

Biochemical Pharmacology

Year:

1987

Language:

english

File:

PDF, 726 KB

english, 1987

8

Tumour cells in metastatic deposits with altered sensitivity to natural killer cells

Colin G. Brooks, Graham R. Flannery, Neville Willmott, Eric B. Austin, Susan Kenwrick, Robert W. Baldwin

Journal:

International Journal of Cancer

Year:

1981

Language:

english

File:

PDF, 718 KB

english, 1981

9

Correlation between tumour drug disposition and the antitumour activity of doxorubicin-loaded microspheres: implications for the drugs' in vivo mechanism of action

Jeffrey Cummings, Neville Willmott, Elaine C. Marley, John F. Smyth

Journal:

Biochemical Pharmacology

Year:

1993

Language:

english

File:

PDF, 410 KB

english, 1993

10

Determination of anthracycline purity in patient samples and identification of in vitro chemical reduction products by application of a multi-diode array high-speed spectrophotometric detector

Jeffrey Cummings, J.Gilmour Morrison, Neville Willmott

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1986

Language:

english

File:

PDF, 793 KB

english, 1986

11

Disposition kinetics of adriamycin, adriamycinol and their 7-deoxyaglycones in AKR mice bearing a sub-cutaneously growing Ridgway Osteogenic Sarcoma (ROS)

Cummings, Jeffrey, Merry, Stephen, Willmott, Neville

Journal:

European Journal of Cancer and Clinical Oncology

Year:

1986

Language:

english

File:

PDF, 1.08 MB

english, 1986

12

The molecular pharmacology of doxorubicin in vivo

Cummings, Jeffrey, Anderson, Lorraine, Willmott, Neville, Smyth, John F.

Journal:

European Journal of Cancer and Clinical Oncology

Year:

1991

Language:

english

File:

PDF, 603 KB

english, 1991

13

The consequences of doxorubicin quinone reduction in vivo in tumour tissue

Jeffrey Cummings, Neville Willmott, Brigid M. Hoey, Elaine S. Marley, John F. SMyth

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 1.14 MB

english, 1992

14

Comparative cardiotoxicity and antitumour activity of doxorubicin (adriamycin) and 4′-deoxydoxorubicin and the relationship to in vivo disposition and metabolism in the target tissues

Jeffrey Cummings, Neville Willmott, Ian More, David J. Kerr, J.Gilmour Morrison, Stanley B. Kaye

Journal:

Biochemical Pharmacology

Year:

1987

Language:

english

File:

PDF, 604 KB

english, 1987

15

The enzymology of doxorubicin quinone reduction in tumour tissue

Jeffrey Cummings, Lucy Allan, Neville Willmott, Robert Riley, Paul Workman, John F. Smyth

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 1.25 MB

english, 1992

16

Conversion of highly malignant colon cancer from an aggressive to a controlled disease by oral administration of a metalloproteinase inhibitor

Zili An, Xiaoen Wang, Neville Willmott, Surinder K. Chander, Simon Tickle, Andrew J. P. Docherty, Andrew Mountain, Andrew T. Millican, Richard Morphy, John R. Porter, R. Ola Epemolu, Tetsuro Kubota, A

Journal:

Clinical and Experimental Metastasis

Year:

1997

Language:

english

File:

PDF, 953 KB

english, 1997

17

Determination of mitomycin C, 2,7-diaminomitosene, 1,2-cis- and 1,2-trans-1-hydroxy-2,7-diaminomitosene in tumour tissue by high-performance liquid chromatography

Jeffrey Cummings, Linda Chirrey, Neville Willmott, Gavin W. Halbert, John F. Smyth

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1993

Language:

english

File:

PDF, 787 KB

english, 1993

18

The use of electron microscopy and immunocytochemistry to characterise spontaneously-arising, transplantable rat tumors

Hassan M. H. Kamel, Neville Willmott, Anne Marie McNicol, Peter G. Toner

Journal:

Virchows Archiv B Cell Pathology Zell-pathologie

Year:

1989

Language:

english

File:

PDF, 2.91 MB

english, 1989

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